Host Ophira Eisenberg welcomes two brave contestants to the puzzle hot seat. Excitement? Nerves? You bet. Josh Rogosin/NPR hide caption

itoggle caption Josh Rogosin/NPR

The Human Guinea Pig

Hear about one man's quests to read the encyclopedia from A to Z, live his life according to the Bible, and achieve bodily perfection—author A.J. Jacobs. How do you quiz the V.I.P. who knows it all?