A Depression-era Appalachian farm wife is branded as a witch by her fundamentalist husband when she bonds with a USDA agent who has traveled to the North Carolina mountains to instruct regional families on how to modernize their homes and farms.
When she returns with her sister Jane to their Ohio hometown after their father falls ill, New York magazine editor Lizzy Bennett confronts her younger sisters' football fan girl antics, a creepy cousin's unwanted attentions and the infuriating standoffish manners of a handsome neurosurgeon.
Disgraced when her village's mysterious healer, who she loved and begged to help her have a child, is arrested as a war criminal, Fidelma flees to England to take migrant work only to confront her nemesis at a tribunal.
An intelligent and dynamic woman who attracts attention wherever she goes and enjoys life with her husband and newborn daughter is astounded by her cancer diagnosis, which pits her family against a difficult healthcare system, well-meant intentions and other stressors that threaten her health and marriage.
While biding her time until she can have weight-loss surgery, Plum joins an underground community of empowered women and agrees to a series of challenges, including work with a group that stages anti-misogyny terrorist acts.