Dexter (Michael C. Hall) grapples -- both literally and emotionally -- with an overwhelming loss in the premiere episode of Dexter. Sonja Flemming/Showtime hide caption

itoggle caption Sonja Flemming/Showtime

Arrested Development star Will Arnett plays a wealthy playboy in the Fox series Running Wilde. David Bianculli says he's not impressed by the pilot, but out of an excess of hope, he'll stick with the show for a few more episodes. Ed Araquel/Fox hide caption

itoggle caption Ed Araquel/Fox

Step Right Up: The new HBO series Boardwalk Empire is set in 1920s Atlantic City, where corruption flows more freely than the Prohibition-banned booze. Craig Blankenhorn hide caption

itoggle caption Craig Blankenhorn

A New Orleans citizen waves the city's flag in a scene from Spike Lee's documentary If God Is Willing and Da Creek Don't Rise. Charley Varley / HBO hide caption

itoggle caption Charley Varley / HBO

Laura Linney plays a suburban mom who discovers she has cancer in The Big C. "She's the reason to watch," says critic David Bianculli. Jordin Althaus/Showtime hide caption

itoggle caption Jordin Althaus/Showtime

Max Headroom (Matt Frewer) appeared in music videos, a feature film, a TV series and commercials for products like New Coke. Shout Factory hide caption

itoggle caption Shout Factory

Will Travers (James Badge Dale) is a brilliant intelligence analyst with a tragic past — who can quickly spot patterns emerging in seemingly random things. AMC hide caption

itoggle caption AMC

Jon Hamm returns to the screen as Don Draper, the 1960s ad man at the center of Mad Men. AMC hide caption

itoggle caption AMC

Over four months, ABC News followed doctors, nurse and patients at three hospitals in Boston. ABC hide caption

itoggle caption ABC

Fangtastic Voyage: The cast of True Blood lounges in the bayou of Louisiana, where the show is set. The vampire soap's third season begins Sunday. HBO hide caption

itoggle caption HBO

The Lost cast — including Josh Holloway, Evangeline Lilly and Jorge Garcia — put the capstone on a six-year story arc with a 2 1/2-hour finale that critic David Bianculli found satisfying on more than one level. ABC hide caption

itoggle caption ABC

This short-horned chameleon in Madagascar stars in "Reptiles & Amphibians," one of the 11 segments of the Discovery Channel natural history series Life. It premieres simultaneously on TLC, Animal Planet, Science Channel, Investigation Discovery, Planet Green and Discovery Health Channel at 8 p.m. EDT on Sunday, March 21. Inaki Relanzon/naturepl.com/Discovery Channel/BBC hide caption

itoggle caption Inaki Relanzon/naturepl.com/Discovery Channel/BBC

Timothy Olyphant plays a U.S. marshal who gets transferred back to his Kentucky hometown after outdrawing and killing a bad guy in Miami. FX/Sony hide caption

itoggle caption FX/Sony