In House of Cards, Kevin Spacey plays Frank Underwood, a politician who climbs to power using ruthless manipulation. Underwood's wife is Claire, played by Robin Wright. David Giesbrecht/Courtesy of Netflix hide caption

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In American Odyssey, Anna Friel plays Sgt. Odelle Ballard, who is stationed in Mali. After her team is killed, she finds herself running for her life — which includes disguising herself as a man. Keith Bernstein/NBC hide caption

itoggle caption Keith Bernstein/NBC

"I'm not one of those who will ever say to you 'No regrets.' I have serious regrets," says actress Kate Mulgrew. "And I think most thoughtful people do, if they live a life as I have lived mine, with a great deal of abandon and passion." Diane Bondareff/Invision/AP hide caption

itoggle caption Diane Bondareff/Invision/AP

As the new season of Game of Thrones begins, Tyrion Lannister (played by Peter Dinklage) is on the run after killing his manipulative father. HBO hide caption

itoggle caption HBO