Volunteers search for needles and other drug paraphernalia along Church Street in Austin, Ind., in April. The region has recorded 142 new HIV cases since December, according to the state, in an outbreak tied to injected-opioid use. Seth Herald/Nurphoto/Corbis hide caption

itoggle caption Seth Herald/Nurphoto/Corbis

Work partners Jon Chintanaroad (left) and Mike Prestano are all smiles now, but founding a tech startup together threatened their friendship — and their business. April Dembosky/KQED hide caption

itoggle caption April Dembosky/KQED

Science-based guidelines say there's no benefit to getting an EKG of heart activity before routine cataract surgery — even if the patient is old. But most doctors order such tests anyway. Bull's Eye/ImageZoo/Corbis hide caption

itoggle caption Bull's Eye/ImageZoo/Corbis

The U.S. Preventive Services Task Force recommends mammograms every other year, while the American Cancer Society endorses annual scans. Kari Lehr/Image Zoo/Corbis hide caption

itoggle caption Kari Lehr/Image Zoo/Corbis