In Dallas Buyers Club, Jared Leto plays Rayon, a transgender woman who is HIV-positive and struggling with a drug habit. "I always saw Rayon as someone who wanted to live ... life as a woman, not just someone who enjoyed putting on women's clothing," Leto says. Anne Marie Fox/Focus Features hide caption

itoggle caption Anne Marie Fox/Focus Features

Canadian astronaut Chris Hadfield has spent a total of six months in space. In his new book, he writes that getting to space took only "8 minutes and 42 seconds. Give or take a few thousand days of training." NASA/Courtesy of Little, Brown and Company hide caption

itoggle caption NASA/Courtesy of Little, Brown and Company

"[Lou Reed] really saw the beauty of life, and wanted to be a person who could live in that beauty as often as possible," longtime publicist Bill Bentley says. Karl Walter/Getty Images hide caption

itoggle caption Karl Walter/Getty Images

Claroscuro showcases the range of Anat Cohen's influences, from New Orleans-style jazz to the music of Brazil. Courtesy of the artist hide caption

itoggle caption Courtesy of the artist

Chiwetel Ejiofor plays Solomon Northup, a free black man in upstate New York who was kidnapped into slavery in 1841 and won his freedom 12 years later. The film 12 Years a Slave is an adaptation of Northup's 1853 memoir. Jaap Buitendijk/Fox Searchlight hide caption

itoggle caption Jaap Buitendijk/Fox Searchlight

12 Years a Slave, starring Chiwetel Ejiofor, is based on an 1853 memoir by Solomon Northup, a free black man in upstate New York who was kidnapped into slavery in 1841. Jaap Buitendijk/Fox Searchlight hide caption

itoggle caption Jaap Buitendijk/Fox Searchlight

Tea Party and conservative leaders including Sen. Ted Cruz, Rep. Michele Bachmann and Sen. Mike Lee gather for a press conference on Capitol Hill in May. Brendan Smialowski/AFP/Getty Images hide caption

itoggle caption Brendan Smialowski/AFP/Getty Images

On Tuesday night, PBS' Frontline will investigate how decades of antibiotic overuse has led to the emergence of drug-resistant superbugs. Courtesy of Centers for Disease Control and Prevention hide caption

itoggle caption Courtesy of Centers for Disease Control and Prevention

John Foster Dulles (right) is greeted by his brother Allen Welsh Dulles on his arrival at LaGuardia Field in New York City in 1948. Jacob Harris/AP hide caption

itoggle caption Jacob Harris/AP

An employee walks through an aisle at Amazon.com's 1.2 million-square foot fulfillment center in Phoenix, Ariz., in November 2012. Ross D. Franklin/AP hide caption

itoggle caption Ross D. Franklin/AP