Actor John Krasinski spent 2 1/2 years in New York trying to get his acting career off the ground. After landing a few commercials and some "off- off- off-Broadway" plays, he was about to call it quits. But his mother encouraged him to stick it out a little while longer, and three weeks later, he landed the role of Jim on The Office. Matt Sayles/Matt Sayles/Invision/AP hide caption

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Fresh Air Weekend: John Krasinski; Lydia Loveless' 'Real'; The Aging Electrical Grid

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Billy Eichner and Julie Klausner quip about show business in Difficult People. Linda Kallerus/Hulu hide caption

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Fresh Air Weekend: Julie Klausner; 'War Dogs'; Rebalancing The 'Microbes Within Us'

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In her latest film, Streep plays Florence Foster Jenkins, an heiress and socialite who didn't let her less-than-great voice stop her from becoming an opera singer. Nick Wall/Paramount Pictures hide caption

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Fresh Air Weekend: Meryl Streep; A Novel Take On Gymnastics; Colson Whitehead

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Jay McInerney is the author of four books, including the 1984 semi-autobiographical novel, Bright Lights, Big City. Michael Lionstar/Knopf hide caption

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Fresh Air Weekend: Jay McInerney; Düsseldorf's Musical Influence; Comic Ali Wong

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Before becoming an actor, Michael K. Williams worked as a background dancer for performers like Madonna and George Michael. Taylor Jewell/Invision/AP hide caption

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Fresh Air Weekend: Michael K. Williams; A Dystopian 'Natural Way'; Sharon Jones

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Mike Birbiglia says his new film, Don't Think Twice, is like a "Big Chill-type comedy set in the world of an improv theater." Bryan Bedder/Getty Images hide caption

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Fresh Air Weekend: Comic Mike Birbiglia; 'Zero Day'; 'Veep' Showrunner David Mandel

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Comedy writer Jessi Klein speaks at the Tribeca Film Festival in 2015. Klein has also written for Saturday Night Live and Transparent. Robin Marchant/Getty Images for the 2015 Tribeca Film Festival hide caption

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Fresh Air Weekend: Christopher Eccleston; 'Underground Airlines'; Comic Jessi Klein

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Robert F. Kennedy is remembered as a liberal icon, but biographer Larry Tye says his views changed over the course of his career. Random House hide caption

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Fresh Air Weekend: 'Bobby Kennedy'; Allen Toussaint's New Album; Rethinking Addiction

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Fresh Air Weekend: Broadway's Barbara Cook: The 'Vanishing Middle Class'; Matt Ross

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Tony Hale plays Gary Walsh, the personal assistant to Selina Meyer, on the HBO series, Veep. Lacey Terrell/HBO hide caption

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Fresh Air Weekend: 'Veep' Actor Tony Hale; Sobriety And Sex; 'What A Fish Knows'

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O.J. Simpson returns to Rich Stadium for his induction into the Buffalo Bills Wall of Fame in 1980. The five-part documentary series, O.J.: Made in America, is available to stream from ESPN. M. Osterreicher/ESPN Films hide caption

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Fresh Air Weekend: 'O.J.: Made In America'; Margaret Glaspy's Album; 'Sweetbitter'

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Adrienne Warren and company perform "I'm Just Wild About Harry" in the musical Shuffle Along, one of five shows Scott Rudin is currently producing on Broadway. Julieta Cervantes/Courtesy of O+M Co. hide caption

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Fresh Air Weekend: Producer Scott Rudin; William Bell's New Album; 'Silicon Valley'

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Akiva Schaffer, Andy Samberg and Jorma Taccone play the hip-hop trio The Style Boyz in the film Popstar: Never Stop Never Stopping. Glen Wilson/Universal Studios hide caption

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Fresh Air Weekend: The Lonely Island; Paul Simon's New Album; The Science Of Warfare

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In the fourth season of the IFC show Maron, Marc Maron's character becomes addicted to opioids and loses his house, cats and podcast. Tyler Golden/IFC hide caption

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Fresh Air Weekend: Marc Maron; Reconsidering Millennial Speak; Susan Silverman

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Kenya Barris is the creator and showrunner of the ABC comedy series, Black-ish. Danny Moloshok/Invision/AP hide caption

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Fresh Air Weekend: Kenya Barris; 'A Bigger Splash'; Novelist Viet Thanh Nguyen

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