Lisa Donovan spoofs the film 300 in a 2007 YouTube video that pits her against a FedEx guy. Donovan's videos became so successful, she was able to make a living off selling ads on them. via YouTube hide caption

itoggle caption via YouTube

Children portray drug lords, corrupt police officers and human traffickers in "Niños Incómodos," which was viewed more than 1.8 million times in one week on YouTube. YouTube hide caption

itoggle caption YouTube

Republican presidential candidate former Massachusetts Gov. Mitt Romney, right, makes a point as Texas Gov. Rick Perry listens, during a debate in Orlando, Fla. Phelan M. Ebenhack/AP hide caption

itoggle caption Phelan M. Ebenhack/AP