The drug sold as K2, spike, spice or "synthetic marijuana" may look like dried marijuana leaves. But it's really any of a combination of chemicals created in a lab that are then sprayed on dried plant material. Spencer Platt/Getty Images hide caption

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Heroin sold in the U.S., like this dose confiscated in Alabama last fall, is often cut with other drugs. Tamika Moore/ hide caption

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Cover art from Stoned. Current hide caption

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Shannon Rivers, a member of the Akimel O'odham tribe, lights a fire for the purification ceremony at the Coconino County jail. Inmates will help him put blankets over the sweat lodge structure, place heated rocks inside and pour water over them. Laurel Morales/KJZZ hide caption

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Needle exchange programs, like this one in Portland, Maine, offer free, sterile syringes and needles to drug users. The programs save money and lives, health officials say, by curtailing the spread of bloodborne infections, such as hepatitis and HIV. Robert F. Bukaty/AP hide caption

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Workplace drug testing for marijuana may need updating in light of changing laws, a case before the Colorado Supreme Court suggests. Kai-Huei Yau/MCT/Landov hide caption

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A man smokes marijuana outside Uruguay's parliament in Montevideo on Wednesday, where lawmakers in the lower house debated and passed a bill that would legalize marijuana and regulate its production and distribution. Matilde Campodonico/AP hide caption

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The United States Supreme Court: a temple to complexity and self-reinforcing feedback loops? Chip Somodevilla/Getty Images hide caption

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The number of new drug shortages each year in the U.S., from 2001 through Dec. 21, 2012. University of Utah hide caption

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