Ruby Corado, second from right, and Selena Cruz whip their hair around playfully while joking with Lazema Mills, left, and Giselle Gartzog, right, at Casa Ruby, a drop-in and service center for transgender people in Washington, D.C. Through the center, Corado helps people find housing, medical care and get food. Lexey Swall/GRAIN for NPR hide caption

itoggle caption Lexey Swall/GRAIN for NPR

Vanity Fair's Twitter page shows its July cover with Caitlyn Jenner. The issue and photo shoot had to be planned in secret. Mladen Antonov/AFP/Getty Images hide caption

itoggle caption Mladen Antonov/AFP/Getty Images

Ruby Corado runs Casa Ruby, a drop-in and service center for transgender people in Washington, D.C. Through the center, Corado helps people find housing, medical care and get food. Corado also has 22 beds in transitional housing for transgender adults and youth who would otherwise be homeless. Lexey Swall/GRAIN for NPR hide caption

itoggle caption Lexey Swall/GRAIN for NPR

Chase Culpepper, 17, was told by DMV officials that she was not allowed to wear makeup in her license photo. The transgender teen sued the federal government for sex discrimination and violating her free speech rights. Courtesy of Transgender Legal Defense & Education Fund hide caption

itoggle caption Courtesy of Transgender Legal Defense & Education Fund

Aydian Dowling is currently leading the annual "Ultimate Guy" contest held by Men's Health magazine. If he wins, he will be the first trans man to appear on the cover. Jason Robert Ballard/FTM Magazine hide caption

itoggle caption Jason Robert Ballard/FTM Magazine

Michaela leans on her mother, Dee, while talking to Dr. Karin Selva about puberty suppression. Kristian Foden-Vencil/Oregon Public Broadcasting hide caption

itoggle caption Kristian Foden-Vencil/Oregon Public Broadcasting

Shane Fairchild (left) tells his friend Sayer Johnson that his late wife, Blue Bauer, was "the only person I ever met that ever treated me like I was me." StoryCorps hide caption

itoggle caption StoryCorps

When Alexis Paige lost her job, she was afraid she would have to discontinue her estrogen treatments. That can't happen now under the Oregon Health Plan. Cree Jude Gordon/Courtesy Alexis Paige hide caption

itoggle caption Cree Jude Gordon/Courtesy Alexis Paige
Katherine Streeter for NPR

Amy Landecker and Jeffrey Tambor are two of the stars of Transparent, in which Tambor's character comes out as transgender to her three adult children. Beth Dubber/Amazon Studios hide caption

itoggle caption Beth Dubber/Amazon Studios