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The CRISPR enzyme (green and red) binds to a stretch of double-stranded DNA (purple and red), preparing to snip out the faulty part.
Illustration courtesy of Jennifer Doudna/UC Berkeley
June 26, 2014 This technique for manipulating genes borrows a strategy from the way bacteria fight viruses. It's still experimental, but the possibilities excite medical researchers hoping to tailor treatments.
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Red blood cells are normally shaped like doughnuts, but sickle cells (purple) are flattened and clump together.
July 17, 2013 The number of babies born with the life-threatening disease will climb by a third in the next 40 years, scientists say. The vast majority of sickle cell cases will occur in developing countries, which don't have the resources to treat deadly complications arising from the genetic disorder.
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Nurse Corean McClinton, left, talks about pain management with Sherry Webb at the Sickle Cell Disease Center in the Truman Medical Center, in Kansas City, Mo., in 2007.
Dick Whipple/Associated Press
January 24, 2013 Patients with the blood disorder can experience severe pain. But when they arrive at the emergency room seeking help, health care personnel often think their requests for narcotics are a sign of addiction. Nursing professor Paula Tanabe is helping to illuminate the problem and improve treatment.
January 26, 2012 The leading group of doctors specializing in blood disorders says it opposes the NCAA's screening program for sickle cell trait in college athletes. The doctors say it overlooks other, more common factors in exercise-related deaths and is not a comprehensive solution.
January 4, 2012 When the Pittsburgh Steelers start the NFL playoffs with a road game in Denver's Mile High Stadium Sunday, they'll do it without free safety Ryan Clark. That's because Clark, who has 100 tackles and the confidence of his coaches, also has sickle cell trait, which can cause severe complications at high altitudes.
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