George McCann has been diagnosed with a subtype of bipolar disorder called the "fear of harm" profile, and finds that a prescribed dose of ketamine every few days alleviates his symptoms. Michael Rubenstein for NPR hide caption

toggle caption Michael Rubenstein for NPR

A rat neuron before (top) and after (bottom) ketamine treatment. The increased number of orange nodes are restored connections in the rat's brain. Ronald Duman/Yale University hide caption

toggle caption Ronald Duman/Yale University

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