Lipitor and other statin drugs are among the most commonly prescribed drugs in the United States. Mel Evans/AP hide caption toggle caption Mel Evans/AP Shots - Health News Tired Of Taking Statins? You're Not Alone. April 3, 2013 A study of statin use in the real world found that 17 percent of patients taking the pills reported side effects, including muscle pain, nausea, and problems with their liver or nervous system. Many of those people quit taking the pills, at least temporarily.