Sales of prescription opioid painkillers have quadrupled since 1999, according to the Centers for Disease Control and Prevention. Rich Pedroncelli/AP hide caption

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Publicity from Vermont Gov. Peter Shumlin's State of the State address last January drove up demand for addiction treatment in the state. Andy Duback/AP hide caption

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Katherine Streeter for NPR

Bryan McDonel and his father, Mike, both served multiple tours in Iraq with the National Guard. Bryan was first prescribed painkillers before his deployment, and his dependence on medication prompted a downward spiral. Quil Lawrence/NPR hide caption

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Several states distribute Naloxone hydrochloride, also called Narcan, to treat opium-based drug overdoses. But only one company manufactures the drug, and the price has spiked in recent years. Toby Talbot/AP hide caption

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