Roughly 27 million Americans took prescription antidepressants in 2005, making them the most commonly prescribed class of medications in America. Ira Flatow and guests discuss depression, from how it's diagnosed and treated to how antidepressants stack up against psychotherapy and placebos. More information.
Gary Greenberg, author, Manufacturing Depression: The Secret History of a Modern Disease; freelance journalist for Harper's, The New Yorker and Mother Jones; practicing psychotherapist, New London, Conn.
Peter Kramer, MD, author, Against Depression; clinical professor of psychiatry and human behavior, Brown University, Providence, R.I.