Ken Rudin, political editor, NPR
Anna Greenberg, senior vice president and principal, Greenberg Quinlan Rosner
Alex Vogel, partner, Mehlman Vogel Castagnetti
There's still another major round of primaries left in 2010, but the true political junkies have their eyes locked on November's midterm elections. And the top issues seem clear: the economy, tax cuts, Afghanistan, health care, gay marriage and immigration.