From NPR News, this is ALL THINGS CONSIDERED. I'm Melissa Block.


And I'm Robert Siegel.

Scientists in California have been studying a group of people with a remarkable musical talent. It's called absolute pitch, also known as perfect pitch.

People with absolute pitch can instantly identify any musical note. The California researchers have been looking for people with this skill in order to understand its genetic basis.

And here with our report is NPR's Joe Palca who is making his worldwide concert debut from Studio 4A on NPR's Steinway grand piano.

JOE PALCA: Thank you, Robert.

(Soundbite of piano note playing)

PALCA: Now most people can identify that as a note on a piano, but there'll be some people who just heard that note, and without even thinking about it, they'll know that it was the A above middle C — at least if this piano is properly tuned.

Dennis Drayna is a geneticist at the National Institute on Deafness and Other Communication Disorders. He says people with absolute pitch can identify notes on a piano the same way most of us can identify colors.

Dr. DENNIS DRAYNA (Geneticist, National Institute on Deafness and Other Communication Disorders): And we can always identify red and it's obvious what's red, and it's obvious what's pink, and we usually don't confuse the two. People with absolute pitch have an analogous ability for their ear.

PALCA: To find people with this ability, geneticist Jane Gitschier turned to the Internet. She and her colleagues at the University of California, San Francisco, created a Web page where people could test their pitch abilities.

Dr. JANE GITSCHIER (Geneticist, University of California - San Francisco): People are given an auditory frequency.

PALCA: Like this, for example.

(Soundbite of tone)

Dr. GITSCHIER: And then they have to click on a little keyboard on the Web to tell us what note they think it is.

PALCA: That was a C, in case you don't have absolute pitch.

As she reports in this week's Proceedings of the National Academy of Sciences, 2,213 individuals took her test.

Dr. GITSCHIER: We had two different populations of people. We had people who scored phenomenally well, and we had people who were throwing darts at the problem.

PALCA: In other words, they were guessing.

Now, even the people who demonstrated absolute pitch did make a few mistakes. When Gitschier analyzed those mistakes, she found something surprising.

Dr. GITSCHIER: The note they err on most often is G sharp.

PALCA: Why G sharp? Well, Gitschier has a hypothesis.

(Soundbite of orchestra tuning)

PALCA: When an orchestra tunes before a concert, everyone tunes to a single note — A. But A can actually be different frequencies. In the United States, A is typically 440 vibrations per second or 440 hertz.

(Soundbite of tone)

PALCA: And there's a range. According to Gitschier, the Berlin Philharmonic tunes to an A at 446 hertz.

(Soundbite of tone)

PALCA: And some orchestras specializing in early music tune to an A as low as 415 hertz.

(Soundbite of tone)

PALCA: And 415 is right where G sharp would be if you tune to one of the higher pitched A's.

Dr. GITSCHIER: So perhaps, people with absolute pitch have learned or incorporated this spread of tuning frequencies into this cluster that they call A.

PALCA: Knowing more about people with absolute pitch will be essential to finding the genes involved. Gitschier has already begun collecting DNA from her subjects recruited on the Internet.

There's one other curious thing Jane Gitschier discovered in her study.

Dr. GITSCHIER: Our results clearly show that as people get older, they are perceiving things sharper than they did when they were younger.

PALCA: So a C sounds like a C sharp.

It's nice to know something gets sharper as we age.

Joe Palca, NPR News, Washington.

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