Copyright ©2012 NPR. For personal, noncommercial use only. See Terms of Use. For other uses, prior permission required.

AUDIE CORNISH, HOST:

From NPR News, this is ALL THINGS CONSIDERED. I'm Audie Cornish.

ROBERT SIEGEL, HOST:

And I'm Robert Siegel. Cats come with a variety of distinctive coat patterns. Some have stripes, some blotches and some come in solid colors. Well, now scientists have figured out that some of the genetic pathways that explain how that happens. And, as odd as this may seem, knowing the genes involved in cat coloration may teach us something about why humans get sick. NPR science correspondent, Joe Palca, explains.

JOE PALCA, BYLINE: Scientists have identified 37 different species of cats living on Earth today. And a few years ago, they worked out the genetics of where those cats all came from.

STEPHEN O'BRIEN: The modern cats descended from a middle size cat, weighed about 20, 30 pounds that wandered around Asia 10 million years ago.

PALCA: Stephen O'Brien has spent a good fraction of his career studying cat genetics. He says in the 10 million years since cats started wandering out of Asia, they have evolved into eight different lineages. For example, there's a group related to the roaring cats, like lions and tigers.

O'BRIEN: The group related to the house cat, the group related to the ocelots, a group that include the cheetah and the puma. And that gave us a backdrop for trying to get at changes that occurred in those lineage with respect to the genes that are allowing one cat to do this...

(SOUNDBITE OF CAT MEOW)

O'BRIEN: Another cat to do that...

(SOUNDBITE OF ROAR)

PALCA: Nice, kitty. Despite these differences, cats tend to look like cats, right down to their coloration.

O'BRIEN: Some cats are spotted, some cats have stripes, some cats have what we call blotches. And other cats don't have any of that, they just have a black or a lion-like color.

PALCA: O'Brien and some of his colleagues at the Hudson Alpha Institute for Biotechnology in Huntsville, Alabama, decided to try to figure out which genes are involved in making these color patterns. And now they've found the three genes that appear to play the biggest role. They report their results in the latest issue of the journal Science. Now, you may be thinking at this point, so what? Why waste time researching something as trivial as the genetics of cat color? O'Brien has heard that question.

O'BRIEN: Often when you're asked to justify it in terms of some medical benefit or something like that, it's a very torturous exercise.

PALCA: He admits this work might just be important for understanding the genetics of cat coloration. On the other hand...

O'BRIEN: It's curious that they have this kind of variation in not only in cats, but we also have this kind of variation even in humans.

PALCA: Different skin colors, different hair colors. And O'Brien says the way genes related to coloration have evolved suggest they may be important for something more fundamental than outward appearance. Some researchers believe these genes may also be involved in resistance to infectious diseases. Cat coloration genes and human diseases? Well, maybe. Joe Palca, NPR News, Washington.

Copyright © 2012 NPR. All rights reserved. No quotes from the materials contained herein may be used in any media without attribution to NPR. This transcript is provided for personal, noncommercial use only, pursuant to our Terms of Use. Any other use requires NPR's prior permission. Visit our permissions page for further information.

NPR transcripts are created on a rush deadline by a contractor for NPR, and accuracy and availability may vary. This text may not be in its final form and may be updated or revised in the future. Please be aware that the authoritative record of NPR's programming is the audio.

Comments

 

Please keep your community civil. All comments must follow the NPR.org Community rules and terms of use, and will be moderated prior to posting. NPR reserves the right to use the comments we receive, in whole or in part, and to use the commenter's name and location, in any medium. See also the Terms of Use, Privacy Policy and Community FAQ.