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NPR's Up First is the news you need to start your day. The three biggest stories of the day, with reporting and analysis from NPR News — in 10 minutes. Available weekdays by 6 a.m. ET, with hosts Rachel Martin, Noel King and Steve Inskeep. Now available on Saturdays by 8 a.m. ET, with hosts Lulu Garcia-Navarro and Scott Simon. Subscribe and listen, then support your local NPR station at donate.npr.org.

Most Recent Episodes

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March 23, 2021

Colorado Shooting, AstraZeneca Data, Biden On Infrastructure

March 23, 2021 • Ten people were killed when a gunman opened fire at a Colorado supermarket. Federal officials say an independent panel of experts said the AstraZeneca vaccine's Phase 3 trial data may have relied on "outdated information". And, the Biden team's next legislative push would boost infrastructure.

Colorado Shooting, AstraZeneca Data, Biden On Infrastructure

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March 22, 2021

AstraZeneca Study, Miami Beach Curfew, Biden's Immigration Policies

March 22, 2021 • The results of a new efficacy study on the AstraZeneca vaccine could pave the way for a Food and Drug Administration decision on whether the vaccine can be used in the United States. The city of Miami Beach is under a curfew to try to mitigate crowds of rowdy spring breakers. And, the Biden administration is struggling to address the developing migration crisis at the country's southern border.

AstraZeneca Study, Miami Beach Curfew, Biden's Immigration Policies

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March 21, 2021

BONUS: Planet Money Buys A Superhero

March 21, 2021 • NPR's Planet Money podcast has been thinking a lot about superheros, not just as entertainment but as economic forces in the world. So they set out on the epic quest to try to make one.

BONUS: Planet Money Buys A Superhero

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March 20, 2021

Atlanta Victims Details, New CDC School Guidance, Vaccine Hesitancy Lessening

March 20, 2021 • President Biden and Vice President Harris express grief in Atlanta, as there details emerge about the 8 people killed in Tuesday's shootings. The CDC says some students can be 3 feet apart in schools, rather than previous guidance of 6. Surveys of Black and Latinx Americans show more intend to get COVID vaccines now, a change from a few months ago.

Atlanta Victims Details, New CDC School Guidance, Vaccine Hesitancy Lessening

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March 19, 2021

AstraZeneca Vaccine, Biden Heading to Georgia, FBI Director On Extremism

March 19, 2021 • As the European Medicines Agency determines that the AstraZeneca COVID-19 Vaccine is safe, the U.S. will send millions of doses of the vaccine to Canada and Mexico. President Biden and Vice President Harris head to Georgia in the aftermath of this week's shootings. And FBI Director Christopher Wray says the threat of right-wing extremism is growing.

AstraZeneca Vaccine, Biden Heading to Georgia, FBI Director On Extremism

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March 18, 2021

GEORGIA SHOOTING, MIGRATION CRISIS, LIVER DISEASES INCREASE

March 18, 2021 • Two police departments in Georgia are investigating the killings of eight people, six of them Asian women, by a 21 year-old white man. President Biden hopes to address the migration crisis at its roots in Central America. And, serious liver diseases are increasing, especially in young women.

GEORGIA SHOOTING, MIGRATION CRISIS, LIVER DISEASES INCREASE

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March 17, 2021

Georgia Shootings, Migrant Crisis, Renter Relief

March 17, 2021 • A 21 year-old white man has been arrested in a string of shootings in Georgia that killed eight people, six of them women of Asian descent. Homeland Security Secretary Alejandro Mayorkas says the surge of migrants arriving at the U.S.-Mexico border is on pace to be the largest in two decades. And, COVID relief measures aimed at helping renters could help landlords struggling with mortgage payments as well.

Georgia Shootings, Migrant Crisis, Renter Relief

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March 16, 2021

AstraZeneca Vaccine, Purdue Pharma Bankruptcy, Capitol Riot Arrests

March 16, 2021 • Portugal joins a growing number of European countries to suspend use of the AstraZeneca vaccine temporarily. Opioid maker Purdue Pharma has filed for bankruptcy with a plan to dissolve the company. And two men have been arrested in the assault of Capitol Police Officer Brian Sicknick, who died of his injuries the day after the Jan. 6 insurrection at the Capitol.

AstraZeneca Vaccine, Purdue Pharma Bankruptcy, Capitol Riot Arrests

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March 15, 2021

FEMA Heads To The Border, Cuomo Scandal, COVID-19 Update

March 15, 2021 • The Federal Emergency Management Agency is heading to the border to help process the increased numbers of unaccompanied minors. An aid to New York Governor Andrew Cuomo has been accused of trying to suppress complaints about the Governor. And, as COVID-19 vaccinations hit new records, more Americans are flying than they have since March 2020.

FEMA Heads To The Border, Cuomo Scandal, COVID-19 Update

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March 14, 2021

BONUS: March 11, 2020

March 14, 2021 • This week marked the unofficial one year anniversary of the start of the pandemic. NPR's Morning Edition looks back at March 11, 2020 through the eyes of two frontline workers.

BONUS: March 11, 2020

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