VIDEO: Why Some Coronavirus Variants Are Better At Infecting Humans : Goats and Soda If you imagine viruses as pieces of a jigsaw puzzle, that can help explain what happens when a coronavirus variant comes into contact with human cells.
NPR logo VIDEO: An Easy Way To Understand Coronavirus Variants — Using Puzzle Pieces

VIDEO: An Easy Way To Understand Coronavirus Variants — Using Puzzle Pieces

Video by Xueying Chang, Kaz Fantone, Michaeleen Doucleff and Ben de la Cruz/NPR YouTube

When will the pandemic end? How many more COVID-19 waves will the U.S. go through? Will we go back to "normal" in the fall? All these questions depend largely a one key factor: how the variants behave.

As the virus spreads around the world, it mutates — which all viruses do. Along the way, variant strains emerge. Some of these variants are more effective at infecting humans and spread more quickly. Some variants may be better at evading the immune system and are more likely to cause a second bout of COVID-19.

Variants with these properties have caused massive waves of COVID in Brazil, South Africa, the United Kingdom — and now India. And in our interconnected world, they are already spreading to many other countries.

How does a mutated version of the virus improve its chances of being transmitted to humans? How does it avoid recognition by the immune system? If you imagine viruses as puzzle pieces, as this video does, that can help explain what's happening when a coronavirus variant comes into contact with human cells.