In college, Amylyx cofounders Josh Cohen and Justin Klee dreamed of finding a treatment for diseases like ALS. When their drug's promise did not pan out, they pulled it voluntarily from the market. Amylyx Pharmaceuticals hide caption
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Ady Barkan speaks at the premiere of his documentary Not Going Quietly in August 2021 in Los Angeles. Vivien Killilea/Getty Images for Greenwich Entertainment hide caption
Pat Bennett takes part in a research session, using a brain-computer interface that helps translate her thoughts into speech. Steve Fisch/Stanford University hide caption
Brian Wallach and Sandra Abrevaya at their home in suburban Chicago. Jamie Kelter Davis for NPR hide caption
Singer Roberta Flack, performing during the 52nd annual Grammy Awards in Los Angeles in 2010. Kevin Winter/Getty Images hide caption
People participate in one last ice bucket challenge during the last annual "Plunge 4 Pete" on what would have been Pete Frates 35th birthday on Dec. 28, 2019 in Gloucester, MA. Jessica Rinaldi/Boston Globe via Getty Images hide caption
Participants tip buckets of ice water over their heads as they take part in the World Record Ice Bucket Challenge at Etihad Stadium on Aug. 22, 2014, in Melbourne, Australia. Scott Barbour/Getty Images hide caption
A controversial new drug for ALS that just received FDA approval could add months to patients' lives, but some scientists question whether it actually works. Manuel Balce Ceneta/AP hide caption
ALS drug's approval draws cheers from patients, questions from skeptics
The drugmaker Amylyx is asking the FDA to approve a new medication for ALS, a fatal neurodegenerative disease. It's possible the agency could greenlight the drug by the end of the month. Manuel Balce Ceneta/AP hide caption
FDA seems poised to approve a new drug for ALS, but does it work?
Researchers examined all 19,423 NFL players who took the field for at least one game from 1960 to 2019 in what the scientists said was the largest study of ALS risk in professional football players. Katelyn Mulcahy/Getty Images hide caption
Scientists at the Allen Institute for Brain Science uncovered differences among human brain cells (left) those of the marmoset monkey (middle) and mouse in a brain region that controls movement, the primary motor cortex. Allen Institute for Brain Science hide caption
New brain maps could help the search for Alzheimer's treatments
Once the rules for implementing it are worked out, a bill signed into federal law in December will eliminate the required five-month waiting period for diagnosed ALS patients to begin disability benefits, enabling quicker Medicare coverage as well. LumiNola/Getty Images hide caption
Patients with a fast-progressing form of ALS who got daily doses of an experimental two-drug combination called AMX0035 scored higher on a standard measure of function than patients who didn't get the drug. Zephyr/Science Source hide caption
Drug Combination Slows Progression Of ALS And Could Mark 'New Era' In Treatment
This light micrograph from the brain of someone who died with Alzheimer's disease shows the plaques and neurofibrillary tangles that are typical of the disease. A glitch that prevents healthy cell structures from transitioning from one phase to the next might contribute to the tangles, researchers say. Jose Luis Calvo/ Science Source hide caption
Pete Frates, (seated, center) participates in the Ice Bucket Challenge with Massachusetts Gov. Charlie Baker to raise money for ALS research at the Statehouse in Boston in 2015. Charles Krupa/AP hide caption
Stephanie Rinka in her beach wheelchair at Fort Fisher State Recreation Area, North Carolina. Courtesy of John Rinka hide caption
Sand artist Sudarsan Pattnaik puts final touches on a sculpture in honor of Stephen Hawking at Puri Beach near Bhubaneswar, India, on Wednesday. Asit Kumar/AFP/Getty Images hide caption
Adox and Michaeli with their son, Orion, in the winter of 2015. Courtesy of Christine Gatti hide caption
A Dying Man's Wish To Donate His Organs Gets Complicated
Karen Lorne, diagnosed with Lou Gehrig's disease in July, volunteers weekly with her certified therapy dog, Bailey, at the Ronald McDonald House in Chapel Hill, N.C. Courtesy of Karen Lorne hide caption
Simplified Study Aims To Quickly Test A Long-Shot ALS Treatment
Tom Hiddleston takes the Ice Bucket Challenge. The actor is one of many stars taking part in the campaign to raise money for ALS. via YouTube hide caption