Talk therapy is best for some people; antidepressants are better for others. Scientists say PET scans might help figure out early on what treatment a person needs. iStockphoto.com hide caption toggle caption iStockphoto.com Shots - Health News Could Brain Scans Reveal The Right Treatment For Depression? June 13, 2013 Treating depression is a hit-or-miss process; the first treatment works less than half the time. Scientists say they may be able to use PET brain scans to tell whether antidepressants or cognitive behavioral therapy will work best. But tailored treatments are still far off.