Dr. James P. Allison, University of Texas MD Anderson Cancer Center, poses for a photo in New York in 2015. Allison and Tasuku Honjo have jointly been awarded the Nobel Prize in medicine or physiology.
Some critically ill patients who received a CAR-T cell treatment have remained cancer-free for as long as five years, researchers say. But the price is high.
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"I'm one of the lucky ones," says Judy Perkins, of the immunotherapy treatment she got. The experimental approach seems to have eradicated her metastatic breast cancer."
Courtesy of Judy Perkins
Image of a CAR-T cell (reddish) attacking a leukemia cell (green). These CAR-T lymphocytes are used for immunotherapy against cancer (CAR stands for chimeric antigen receptor). After the proliferation of the CAR-expressing T cells, they are transfused back into the patient and can directly detect the cancer cells carrying the antigen.
Eye of Science/Science Source
Johns Hopkins Hospital in Baltimore opened a six-bed urgent care center next to its infusion center a couple of years ago. Of the patients who land there, about 80 percent are discharged home afterward, rather than needing admission to the hospital.
Courtesy of Johns Hopkins Medicine
Earlier this week, NIH temporarily halted work in the cell therapy lab of Dr. Steven Rosenberg, chief of surgery at the National Cancer Institute, pending a review of safety standards there.
Courtesy of National Cancer Institute