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Angus Cloud arrives in March 2022 at the Vanity Fair Oscar Party in Beverly Hills, Calif. Cloud, the 25-year-old actor who starred as the drug dealer Fezco "Fez" O'Neill on the HBO series "Euphoria," died of an overdose of cocaine, fentanyl and other substances, a Northern California coroner's office said Thursday. Evan Agostini/Evan Agostini/Invision/AP hide caption

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Evan Agostini/Evan Agostini/Invision/AP

A team of volunteers with an Ohio-based nonprofit handed out 2,500 doses of a nasal spray version of naloxone, an overdose reversal drug, at this year's Bonnaroo music festival. Amy Harris/Invision via AP hide caption

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Amy Harris/Invision via AP

A man gets care in an ambulance after overdosing in San Francisco, California. Rachel Bujalski for NPR hide caption

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Rachel Bujalski for NPR

San Francisco's new rapid response teams race to save lives as ODs dramatically rise

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Regina LaBelle is the acting director of the White House Office of National Drug Control Policy. During a Thursday morning briefing, LaBelle said drug overdose deaths were up about 27% in the 12-month period ending in August 2020, compared with the previous year. White House Office of National Drug Control Policy hide caption

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White House Office of National Drug Control Policy

Drug Overdose Deaths Spiked To 88,000 During The Pandemic, White House Says

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Scientists at the Centers for Disease Control and Prevention say fatal drug overdoses nationwide surged roughly 20% during the pandemic, killing more than 83,000 people in 2020. A growing body of research suggests Black Americans have suffered the heaviest toll. Jamiel Law for NPR hide caption

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Jamiel Law for NPR

Drug Overdose Deaths Surge Among Black Americans During Pandemic

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Lights placed as a memorial to COVID-19 victims surround the Lincoln Memorial Reflecting Pool on Jan. 19. Some economists believe deaths tied to alcohol use, drug use and suicides have risen during the pandemic as the isolation felt by many has taken an emotional toll. Alex Brandon/AP hide caption

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Alex Brandon/AP

They Lost Sons To Drug Overdoses: How The Pandemic May Be Fueling Deaths Of Despair

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Alfred Gescheidt/Getty Images

Experts Say Attack On Hunter Biden's Addiction Deepens Stigma For Millions

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