Angus Cloud arrives in March 2022 at the Vanity Fair Oscar Party in Beverly Hills, Calif. Cloud, the 25-year-old actor who starred as the drug dealer Fezco "Fez" O'Neill on the HBO series "Euphoria," died of an overdose of cocaine, fentanyl and other substances, a Northern California coroner's office said Thursday. Evan Agostini/Evan Agostini/Invision/AP hide caption
A team of volunteers with an Ohio-based nonprofit handed out 2,500 doses of a nasal spray version of naloxone, an overdose reversal drug, at this year's Bonnaroo music festival. Amy Harris/Invision via AP hide caption
Mac Miller performs an NPR Tiny Desk Concert on Aug. 1, 2018. Eslah Attar/NPR hide caption
West Point cadets walk on campus at the United States Military Academy in West Point, N.Y. Mel Evans/AP hide caption
A man gets care in an ambulance after overdosing in San Francisco, California. Rachel Bujalski for NPR hide caption
State prisons are grappling with how to deal with an increase in overdoses due to alcohol and drug abuse. David Madison/Getty Images hide caption
Regina LaBelle is the acting director of the White House Office of National Drug Control Policy. During a Thursday morning briefing, LaBelle said drug overdose deaths were up about 27% in the 12-month period ending in August 2020, compared with the previous year. White House Office of National Drug Control Policy hide caption
Scientists at the Centers for Disease Control and Prevention say fatal drug overdoses nationwide surged roughly 20% during the pandemic, killing more than 83,000 people in 2020. A growing body of research suggests Black Americans have suffered the heaviest toll. Jamiel Law for NPR hide caption
Lights placed as a memorial to COVID-19 victims surround the Lincoln Memorial Reflecting Pool on Jan. 19. Some economists believe deaths tied to alcohol use, drug use and suicides have risen during the pandemic as the isolation felt by many has taken an emotional toll. Alex Brandon/AP hide caption
One person has died and a total of 12 people were taken to the hospital after a mass drug overdose in Chico, Calif. Above, syringes of the opiate fentanyl appear at an inpatient pharmacy. Rick Bowmer/AP hide caption