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Esketamine

Patients report that ketamine infusions can be lifesaving, with immediate improvement for severe depression. But dosage and safety measures vary widely at the hundreds of clinics that have opened. Yana Iskayeva/Getty Images hide caption

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Yana Iskayeva/Getty Images

Scientists used light to control the firing of specific cells to artificially create a rhythm in the brain that acted like the drug ketamine enjoynz/Getty Images hide caption

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enjoynz/Getty Images

Scientists Say A Mind-Bending Rhythm In The Brain Can Act Like Ketamine

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In 2019, the FDA approved Spravato for patients with major depressive disorder who hadn't responded to other treatments. Now, the agency is adding patients who are having suicidal thoughts or have recently attempted to harm themselves or take their own lives. Sarah Silbiger/Getty Images hide caption

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Sarah Silbiger/Getty Images

Nasal Spray Is A New Antidepressant Option For People At High Risk of Suicide

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