People are wondering if alcohol in between vaccine doses might have an impact on your body's reaction to the vaccination. Michele Abercrombie/NPR hide caption toggle caption Michele Abercrombie/NPR Goats and Soda Coronavirus FAQs: Can I Drink Between Vaccine Doses? What Is 'Vaccine Efficacy'? March 12, 2021 People who've had dose 1 are wondering ... can I have a few drinks before dose 2 or will that muck things up? Also: Do you really understand the concept of "vaccine efficacy"? It's complicated!