Scientists Grow Parts For Kids With Urinary Damage Scientists have been trying for years to grow replacement parts for defective or damaged organs. Now, a report published in a medical journal tells a success story about fixing the urinary tracts of five young Mexican boys. The procedure could ultimately help thousands of children.

Scientists Grow Parts For Kids With Urinary Damage

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In this part of the program, we're going to look at a couple of promising developments for those who've become disabled. In a moment we'll hear about an eye bank in Seattle that's helping restore vision for people around the world. First, NPR's Richard Knox tells us about researchers who are reporting progress in making new tissue for children who have been in serious accidents.

RICHARD KNOX: This is a success story about five young Mexican boys whose urinary tracts were terribly damaged in car accidents. Researcher Anthony Atala says none of these boys could urinate normally.

ANTHONY ATALA: When they first come in, they have a leg bag that drains urine and they have to carry this bag around with them everywhere they go. And it's also uncomfortable and painful.

KNOX: The first thing they did was to remove a small section of each boy's bladder.

ATALA: The piece of tissue we take is very small - less than one-half the size of a postage stamp.

KNOX: The researchers stitched these made-to-order tissue tubes into the gaps in the boys' urinary systems. That was six years ago. In every case the boys' re- engineered urinary systems are functioning normally.

ATALA: Typically, if you're going to see these structures fail, they can fail early or they can fail late. But if you have them with this long of a follow-up, then you know that they're going to do well over time.

KNOX: Atala says the procedure has transformed the boys' lives.

ATALA: These children now are totally normal children, running around and doing the things they usually do.

KNOX: Dr. Dario Fauzo of Children's Hospital in Boston says the report is encouraging, but it's only a first step.

DARIO FAUZO: We are only talking about five patients, which is certainly not enough for widespread, meaningful conclusions.

KNOX: Fauzo says it's not clear if the implanted cells did the job or stimulated other cells in the boys' systems to heal the damage.

FAUZO: We don't know if the cells that were put in there are still there. But that they did something helpful, it appears they did.

KNOX: Richard Knox, NPR News.

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