Federal Brain Science Project Aims To Restore Soldiers' Memory : Shots - Health News President Obama has launched basic research to help scientists peer deep into the individual nerve circuits in the brain. There's also a more practical effort to restore the memories of injured soldiers by outfitting them with specialized brain implants.

Federal Brain Science Project Aims To Restore Soldiers' Memory

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Now an update on President Obama's plan to explore the mysteries of the human brain. It's been seven months since the president announced his brain initiative. And this week, at the Society for Neuroscience meeting in San Diego, several agencies discussed how they intend to carry out the ambitious plan. NPR's Jon Hamilton reports.

JON HAMILTON, BYLINE: At a news conference, officials from the National Institutes of Health, the National Science Foundation and the Defense Advanced Research Projects Agency, or DARPA, all talked about their roles in the brain initiative. DARPA, which has committed more than $50 million to the effort, offered the clearest plan. Geoffrey Ling says his agency wants to focus on treatments for the sort of brain disorders affecting soldiers that served in Iraq and Afghanistan.

GEOFFREY LING: For DARPA, that is dead-on our focus. That is our constituency.

HAMILTON: So Ling says DARPA will be trying to solve problems including PTSD and traumatic brain injuries.

LING: And injured soldier comes back, has a terribly damaged brain and has lost a significant amount of declarative memory, we would like to restore that memory in that individual.

HAMILTON: DARPA hopes to do that with a device that actually takes over some function of the brain's hippocampus. The agency has already done this in rats. They've even created rats with extraordinary memory. And Ling says the goal is to get a memory restoring device into people quickly. He says DARPA is using the same approach it has used to create a prosthetic arm controlled by the brain.

LING: We went from idea to prototype in 18 months and now we are in the final stages of FDA review, and that means that from idea to product in six years.

HAMILTON: The National Institutes of Health plans to invest $40 million in the BRAIN Initiative over the next year. Story Landis is director of the National Institute of Neurological Disorders and Stroke. She says a major goal will be creating new tools that reveal the function of specific brain circuits.

STORY LANDIS: And we believe that the tools and technologies that will come from this initiative will actually enable all brain scientists to do their work better, faster and with more impact.

HAMILTON: Landis says that could lead to better treatments for people with brain diseases including Parkinson's. She says for several years now, people with Parkinson's have been able to reduce their tremors with a treatment known as deep brain stimulation.

LANDIS: While it works, it's incredibly crude. Imagine if we knew exactly how that circuitry worked. You could design a much better way to do deep brain stimulation.

HAMILTON: But Tom Insel, director of the National Institute of Mental Health, says it's important to remember that the immediate goal of the BRAIN Initiative isn't developing treatments. The goal is understanding the inner workings of the most complex system in the universe.

TOM INSEL: Is that going to give us new diagnostics, new therapeutics? One hopes, but that's not actually the promise here.

HAMILTON: Insel says much of the early work will involve animals, not people. And some big chunks of the work will be done by organizations other than the NIH. For example, the Howard Hughes Medical Institute has agreed to map the entire nervous system of a fruit fly. And the Allen Institute for Brain Science is figuring out how a mouse brain processes visual information.

Insel says he thinks the public will get a lot out of this kind of research, even though the goal isn't curing epilepsy or Alzheimer's disease.

INSEL: The public is interested not just in curing disease, but they're interested in the brain as a way of trying to understand who we are, what makes us different and what is special about the human brain. That's a big question that we don't have a lot of the answers for.

HAMILTON: President Obama has asked for an extra $100 million to help fund the BRAIN Initiative in the next year. But scientists say the effort will accomplish a lot even if that extra money doesn't materialize. Jon Hamilton, NPR News.

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